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抑制剂 & 化合物

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重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T76964 Valanafusp alfa

Valanafusp alfa (AGT-181) 是一种融合了抗人胰岛素受体 (HIR) 和人硬糖苷酶 (IDUA) 的嵌合单克隆抗体的脑穿透重组融合蛋白。该化合物主要应用于粘多糖病 I 型 (MPS I) 的研究领域。

化合物

Valanafusp alfa
Cat.No: T76964
Synonym:
Target:
Species：
Human (20)
Human & Mouse (4)
Mouse (1)
Expression System：
HEK293 Cells (14)
E. coli (8)
P. pastoris (Yeast) (2)
Baculovirus Insect Cells (1)
Tag：
C-His-Avi (8)
C-His (5)
N-6xHis (4)
N-GST (3)
Tag Free (2)
His, GST (1)
N-10xHis (1)
N-10xHis, C-Myc (1)
Cat. No. Product Name Species Expression System
TMPY-00395 Insulin Protein, Human, Recombinant

IDDM1,MODY10,ILPR,IDDM2,IRDN,IDDM,insulin,INS

 Human P. pastoris (Yeast)
INS (Insulin) is a Protein Coding gene. This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. The binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Diseases associated with ...
TMPY-01146 Insulin Receptor Protein, Human, Recombinant (long isoform, His)

HHF5,CD220,insulin receptor

 Human HEK293 Cells
Insulin Receptor Protein, Human, Recombinant (long isoform, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 107 kDa and the accession number is P06213-1.
TMPY-04395 Insulin Receptor Protein, Human, Recombinant (His & GST)

HHF5,insulin receptor,CD220

 Human Baculovirus Insect Cells
Insulin Receptor Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 72.3 kDa and the accession number is P06213-1.
TMPY-01149 Insulin Receptor Protein, Human, Recombinant (short isoform, His)

Insulin Receptor,HHF5,CD220

 Human HEK293 Cells
Insulin Receptor Protein, Human, Recombinant (short isoform, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 106 kDa and the accession number is P06213-2.
TMPY-05283 Insulin Receptor Protein, Human, Recombinant (long isoform, His), Biotinylated

CD220,Insulin Receptor,HHF5

 Human HEK293 Cells
Insulin Receptor Protein, Human, Recombinant (long isoform, His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 107 kDa and the accession number is P06213-1.
TMPH-01094 CELA2A Protein, Human, Recombinant (His)

Chymotrypsin-like elastase family member 2A,CELA2A,ELA2A,Ela...

 Human P. pastoris (Yeast)
Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism. Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and increases insulin sensitivity. CELA2A Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 27.9 kDa and the accession number is P08217.
TMPH-02197 TXNDC5 Protein, Human, Recombinant

Human E. coli
Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide-isomerase deficiency in yeast. TXNDC5 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 36.2 kDa and the accession number is Q8NBS9.
TMPH-01093 CELA2A Protein, Human, Recombinant (E. coli, His)

Elastase-2A,CELA2A,Chymotrypsin-like elastase family member ...

 Human E. coli
Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism. Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and increases insulin sensitivity. CELA2A Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 29.9 kDa and the accession number is P08217.
TMPH-02323 SLC30A8 Protein, Human, Recombinant (His)

Human E. coli
Facilitates the accumulation of zinc from the cytoplasm into intracellular vesicles, being a zinc-efflux transporter. May be a major component for providing zinc to insulin maturation and/or storage processes in insulin-secreting pancreatic beta-cells. SLC30A8 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 43.6 kDa and the accession number is Q8IWU4.
TMPY-06479 Cathepsin H Protein, Human, Recombinant (His)

CPSB,ACC-5,minichain,ACC4,ACC5,cathepsin H,ACC-4

 Human HEK293 Cells
Proinflammatory cytokines decreased the expression of CTSH in human islets and primary rat beta-cells, and overexpression of CTSH protected insulin-secreting cells against cytokine-induced apoptosis. Cathepsin H Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.62 kDa and the accession number is NP_004381.2.
TMPH-02196 TXNDC5 Protein, Human, Recombinant (GST)

Human E. coli
Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide-isomerase deficiency in yeast. TXNDC5 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 63.2 kDa and the accession number is Q8NBS9.
TMPH-01562 IAPP Protein, Human, Recombinant (GST)

Human E. coli
Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. IAPP Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 31.4 kDa and the accession number is P10997.
TMPY-04081 Cathepsin H Protein, Mouse, Recombinant (His)

cathepsin H,AL022844

 Mouse HEK293 Cells
Proinflammatory cytokines decreased the expression of CTSH in human islets and primary rat beta-cells, and overexpression of CTSH protected insulin-secreting cells against cytokine-induced apoptosis. Cathepsin H Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.6 kDa and the accession number is AAA82966.1.
TMPK-01354 IGF2R Protein, Human, Recombinant (His & Avi)

M6P/IGF2R,IGF-II receptor,MPRI,CI-MPR,CD222,MPR 300,M6PR

 Human HEK293 Cells
The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer. IGF2R Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 164.90 kDa and the accession number is P11717.
TMPK-01361 IGF2R Protein, Human, Recombinant (His & Avi), Biotinylated

MPR 300,IGF-II receptor,M6PR,M6P/IGF2R,CD222,MPRI,CI-MPR

 Human HEK293 Cells
The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer. IGF2R Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 164.90 kDa and the accession number is P11717.
TMPK-01353 IGF2R Domain 1-3 Protein, Human, Recombinant (His & Avi)

CI-MPR,MPR 300,MPRI,M6P/IGF2R,M6PR,CD222,IGF-II receptor

 Human HEK293 Cells
The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer. IGF2R Domain 1-3 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 50.50 kDa and the accession number is P11717.
TMPH-01385 GLP1R Protein, Human, Recombinant (His)

Human HEK293 Cells
G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1. GLP1R Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 18.3 kDa and the accession number is P43220.
TMPH-01384 GLP1R Protein, Human, Recombinant (E. coli, His)

Human E. coli
G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1. GLP1R Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 18.3 kDa and the accession number is P43220.
TMPK-01355 IGF2R Domain 1-7 Protein, Human, Recombinant (His & Avi)

IGF-II receptor,CI-MPR,CD222,M6P/IGF2R,MPRI,M6PR,MPR 300

 Human HEK293 Cells
The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer. IGF2R Domain 1-7 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 117.40 kDa and the accession number is P11717.
TMPH-02022 RXFP2 Protein, Human, Recombinant (His & Myc)

Human E. coli
Receptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3). RXFP2 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 21.1 kDa and the accession number is Q8WXD0.
TMPH-01462 HNRNPH1 Protein, Human, Recombinant (GST)

Human E. coli
This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG). HNRNPH1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system...
TMPK-01523 Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Monomer Protein, Human&Mouse, MHC (His & Avi)

WAGR,WT33,AWT1,GUD,RMF,WT1,WIT-2,MHC,NPHS4GUD

 Human & Mouse HEK293 Cells
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, endometrioid, clear cell, and mucinous carcinomas of the peritoneum, fallopian tube, ovary, and endometrium.The Human HLA-A*0201 WT-1 (RMFPNAPYL) complex Protein is a complex of HLA-A*0201 of  the MHC Class I, B2M and RMFPNAPYL peptide of  the WT-1.
TMPK-01534 Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human&Mouse, MHC (His & Avi)

RING12,PSMB9,Proteasome chain 7,RMF,LMP-2,LMP2,MHC,Macropain...

 Human & Mouse HEK293 Cells
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of ma...
TMPK-01522 Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Tetramer Protein, Human&Mouse, MHC (His & Avi)

RMF,WT33,WIT-2,MHC,WAGR,AWT1,GUD,WT1,NPHS4GUD

 Human & Mouse HEK293 Cells
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, endometrioid, clear cell, and mucinous carcinomas of the peritoneum, fallopian tube, ovary, and endometrium.The Human HLA-A*0201 WT-1 (RMFPNAPYL) complex Protein is a complex of HLA-A*0201 of  the MHC Class I, B2M and RMFPNAPYL peptide of  the WT-1.
TMPK-01535 Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Tetramer Protein, Human&Mouse, MHC (His & Avi)

Macropain chain 7,LMP2,Proteasome chain 7,RING12,PSMB9,MHC,R...

 Human & Mouse HEK293 Cells
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of ma...

重组蛋白

Insulin Protein, Human, Recombinant
Cat.No: TMPY-00395
Species: Human
Expression System: P. pastoris (Yeast)
Insulin Receptor Protein, Human, Recombinant (long isoform, His)
Cat.No: TMPY-01146
Species: Human
Expression System: HEK293 Cells
Insulin Receptor Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04395
Species: Human
Expression System: Baculovirus Insect Cells
Insulin Receptor Protein, Human, Recombinant (short isoform, His)
Cat.No: TMPY-01149
Species: Human
Expression System: HEK293 Cells
Insulin Receptor Protein, Human, Recombinant (long isoform, His), Biotinylated
Cat.No: TMPY-05283
Species: Human
Expression System: HEK293 Cells
CELA2A Protein, Human, Recombinant (His)
Cat.No: TMPH-01094
Species: Human
Expression System: P. pastoris (Yeast)
TXNDC5 Protein, Human, Recombinant
Cat.No: TMPH-02197
Species: Human
Expression System: E. coli
CELA2A Protein, Human, Recombinant (E. coli, His)
Cat.No: TMPH-01093
Species: Human
Expression System: E. coli
SLC30A8 Protein, Human, Recombinant (His)
Cat.No: TMPH-02323
Species: Human
Expression System: E. coli
Cathepsin H Protein, Human, Recombinant (His)
Cat.No: TMPY-06479
Species: Human
Expression System: HEK293 Cells
TXNDC5 Protein, Human, Recombinant (GST)
Cat.No: TMPH-02196
Species: Human
Expression System: E. coli
IAPP Protein, Human, Recombinant (GST)
Cat.No: TMPH-01562
Species: Human
Expression System: E. coli
Cathepsin H Protein, Mouse, Recombinant (His)
Cat.No: TMPY-04081
Species: Mouse
Expression System: HEK293 Cells
IGF2R Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-01354
Species: Human
Expression System: HEK293 Cells
IGF2R Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-01361
Species: Human
Expression System: HEK293 Cells
IGF2R Domain 1-3 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-01353
Species: Human
Expression System: HEK293 Cells
GLP1R Protein, Human, Recombinant (His)
Cat.No: TMPH-01385
Species: Human
Expression System: HEK293 Cells
GLP1R Protein, Human, Recombinant (E. coli, His)
Cat.No: TMPH-01384
Species: Human
Expression System: E. coli
IGF2R Domain 1-7 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-01355
Species: Human
Expression System: HEK293 Cells
RXFP2 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-02022
Species: Human
Expression System: E. coli
HNRNPH1 Protein, Human, Recombinant (GST)
Cat.No: TMPH-01462
Species: Human
Expression System: E. coli
Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Monomer Protein, Human&Mouse, MHC (His & Avi)
Cat.No: TMPK-01523
Species: Human & Mouse
Expression System: HEK293 Cells
Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human&Mouse, MHC (His & Avi)
Cat.No: TMPK-01534
Species: Human & Mouse
Expression System: HEK293 Cells
Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Tetramer Protein, Human&Mouse, MHC (His & Avi)
Cat.No: TMPK-01522
Species: Human & Mouse
Expression System: HEK293 Cells
Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Tetramer Protein, Human&Mouse, MHC (His & Avi)
Cat.No: TMPK-01535
Species: Human & Mouse
Expression System: HEK293 Cells
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